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What Are the Side Effects of Testosterone Injections?

Testosterone Side Effects: Common, Severe, Long Term

This side effect is more common in individuals who are already prone to acne. However, acne caused by testosterone cypionate injections usually resolves on its own after the treatment is stopped. There is a wide array of benefits that may be available to men seeking to correct their declining hormone levels. As men age, testosterone typically decreases, causing a range of symptoms that can really put a damper on daily life. Although aging is an inevitable process and only one aspect of low testosterone, there are options available to promote one’s health and wellbeing. Testosterone injections may be a solution if one is seeking to gain more energy, more stamina, greater sexual function, and stronger muscles and bones.

However, there was a higher incidence of pulmonary embolism, acute kidney injury, and atrial fibrillation among men who received testosterone replacement. This isn’t a big deal for most people, he says, and its more common to see it if you’re taking a non-daily treatment like an injection, where you’re getting a higher dose of T in one sitting. Sperm production may or may not go back to normal after stopping treatment, says Dr. Kaminetsky. A 2017 study in Fertility & Sterility found that increasing age and longer length of T-therapy were linked to lower chances of normal sperm recovery. Muscles respond to testosterone, and starting T-therapy can increase muscle mass, says Dr. Morgentaler. That’s because testosterone activates the androgen receptors in muscle tissue to stimulate growth.

These side effects are typically dose-dependent and may vary from person to person. In conclusion, testosterone cypionate injections are a popular form of testosterone replacement therapy for men with low testosterone levels. While they have some potential side effects, such as polycythemia and skin-related issues, they also offer advantages in terms of consistent hormone release and dosage flexibility. It is crucial to weigh the potential risks and benefits and consult with a healthcare professional to determine the most suitable form of TRT for each individual’s needs. Another possible side effect of testosterone cypionate injections is an increase in red blood cell production. Testosterone can stimulate the bone marrow to produce more red blood cells, which can lead to an increase in the thickness or viscosity of the blood. This can increase the risk of blood clots or other cardiovascular complications.

A commercial testosterone product intended for men is another option, but never do this without a prescription from a health care professional. So while I do sometimes prescribe a product meant for guys, it is not convenient, as one must be very precise about the dosage. The FDA alert underscores broader concerns about compounded medications, which the agency does not review or approve. As telehealth services make these products more accessible, experts warn that patients may be unaware of the potential risks.

Between 2001 and 2011, prescriptions for TRT among men 40 years of age or older in the US increased more than threefold, from 0.81% in 2001 to 2.91% in 2011 [Baillargeon et al. 2013]. Testosterone is responsible for many different functions within the body, including sexual performance, physical stamina, emotional wellness, and cognitive function. Therefore, as testosterone levels decrease, these functions can begin to dwindle as well.

From there, it circulates throughout the body, binding to androgen receptors in various tissues and organs. Testosterone injections work by directly supplementing the body with synthetic testosterone, a medication that mimics the effects of naturally produced testosterone. These injections typically contain synthetic testosterone or testosterone injections for men side effects (frescina.com) esters and are administered directly into the muscle tissue, usually in the buttocks or thigh. The FDA also warns that since topical finasteride is applied directly to the skin, it may inadvertently transfer to others through contact, an issue with potentially serious consequences.

Another side effect of testosterone injections therapy is elevated estrogen levels. High levels of testosterone increase circulating estrogen levels in two ways. The first is by displacing estrogen from a serum carrier known as sex hormone-binding globulin (SHBG). The second is by converting free testosterone injections to estradiol (a type of estrogen) in tissues such as the testes, muscle, and bone via a process known as aromatization.

The FDA has approved more than 30 testosterone medications for males but none for females. While testosterone does have an association with masculinizing effects, such as hair growth and acne, nobody reported this in the 36 trials the researchers examined, which included over 8,000 participants in total. However, a significant number of these patients did not have low enough testosterone levels to receive a diagnosis of hypogonadism. Hypogonadism is when the testes are not producing enough testosterone or sperm.

Talk to your care team about the use of this medication in children. A 2020 meta-analysis found that TRT significantly improved depressive symptoms in men with low testosterone. Harvard Health emphasizes that TRT should be tailored to the individual and revisited frequently to minimize risks and optimize outcomes. Yes, TRT has been said to lower sperm count, especially if taken without precautions. That is one reason why some men are prescribed hCG (human chorionic gonadotropin) alongside TRT to maintain testicular function and fertility potential. This blog does not endorse any specific products, services, or treatments. The opinions expressed on this blog are our own and do not necessarily reflect the views of others.